{"id":34328,"date":"2025-12-05T10:44:55","date_gmt":"2025-12-05T02:44:55","guid":{"rendered":"https:\/\/eng.cycu.edu.tw\/?p=34328"},"modified":"2026-01-09T11:14:02","modified_gmt":"2026-01-09T03:14:02","slug":"cycu-professor-yi-chih-hsu-transfers-innovative-nanomedicine-technology-to-accelerate-precision-medicine-translation","status":"publish","type":"post","link":"https:\/\/eng.cycu.edu.tw\/?p=34328","title":{"rendered":"CYCU Professor Yi-Chih Hsu Transfers Innovative Nanomedicine Technology to Accelerate Precision Medicine Translation."},"content":{"rendered":"\n<p>Professor Yi-Chih Hsu of the Department of Biotechnology, CYCU has long specialized in cancer drug delivery systems and nanoparticle-based pharmaceutical formulations. She developed an innovative liposomal drug-encapsulation technology, formally referred to as \u201cliposomal composite drug-loading platform.\u201d<\/p>\n\n\n\n<p>In November 2025, this proprietary technology entered technology transfer to CYCU-affiliated spin-off company Hermez Nanomedicine, Inc. The collaboration achieved a major technology licensing agreement, securing substantial licensing revenue for the university.<\/p>\n\n\n\n<p>Professor Yi-Chih Hsu highlighted that her patented liposomal composite drug-encapsulation technology effectively overcomes major limitations of conventional platinum-based chemotherapies, such as poor solubility and severe systemic toxicity. The platform enables drug nanonization below 50 nm, significantly improves encapsulation efficiency, and achieves tumor-targeted delivery within approximately 50 minutes, thereby enhancing drug accumulation, prolonging circulation time, and improving both efficacy and safety. With 24 patents granted globally\u2014including in the United States, 21 EU countries, Japan, and Taiwan\u2014the technology demonstrates strong international competitiveness and readiness for commercialization. <\/p>\n\n\n\n<p>Hsu\u2019s team further noted that the innovation holds promise for addressing drug resistance, supporting nanocarrier-based formulations, and enabling long-acting release systems. The platform also features a One-Pot, GMP-compliant high-yield manufacturing process, and has successfully completed two years of CMC stability validation, underscoring its robustness and industrialization potential.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1600\" height=\"1200\" src=\"https:\/\/eng.cycu.edu.tw\/wp-content\/uploads\/02-\u4e2d\u539f\u5927\u5b78\u751f\u79d1\u7cfb\u6559\u6388\u8a31\u6bc5\u829d\u7814\u767c\u4e4b\u5275\u65b0\u5948\u7c73\u85e5\u7269\u5e73\u53f0\u6280\u8853\uff0c\u5c07\u6280\u8f49\u4e88\u5929\u60e0\u5948\u7c73\u751f\u91ab\uff0c\u52a0\u901f\u7cbe\u6e96\u91ab\u7642\u7522\u696d\u843d\u5730\u3002.jpg\" alt=\"\" class=\"wp-image-34329\" srcset=\"https:\/\/eng.cycu.edu.tw\/wp-content\/uploads\/02-\u4e2d\u539f\u5927\u5b78\u751f\u79d1\u7cfb\u6559\u6388\u8a31\u6bc5\u829d\u7814\u767c\u4e4b\u5275\u65b0\u5948\u7c73\u85e5\u7269\u5e73\u53f0\u6280\u8853\uff0c\u5c07\u6280\u8f49\u4e88\u5929\u60e0\u5948\u7c73\u751f\u91ab\uff0c\u52a0\u901f\u7cbe\u6e96\u91ab\u7642\u7522\u696d\u843d\u5730\u3002.jpg 1600w, https:\/\/eng.cycu.edu.tw\/wp-content\/uploads\/02-\u4e2d\u539f\u5927\u5b78\u751f\u79d1\u7cfb\u6559\u6388\u8a31\u6bc5\u829d\u7814\u767c\u4e4b\u5275\u65b0\u5948\u7c73\u85e5\u7269\u5e73\u53f0\u6280\u8853\uff0c\u5c07\u6280\u8f49\u4e88\u5929\u60e0\u5948\u7c73\u751f\u91ab\uff0c\u52a0\u901f\u7cbe\u6e96\u91ab\u7642\u7522\u696d\u843d\u5730\u3002-768x576.jpg 768w, https:\/\/eng.cycu.edu.tw\/wp-content\/uploads\/02-\u4e2d\u539f\u5927\u5b78\u751f\u79d1\u7cfb\u6559\u6388\u8a31\u6bc5\u829d\u7814\u767c\u4e4b\u5275\u65b0\u5948\u7c73\u85e5\u7269\u5e73\u53f0\u6280\u8853\uff0c\u5c07\u6280\u8f49\u4e88\u5929\u60e0\u5948\u7c73\u751f\u91ab\uff0c\u52a0\u901f\u7cbe\u6e96\u91ab\u7642\u7522\u696d\u843d\u5730\u3002-1536x1152.jpg 1536w\" sizes=\"(max-width: 1600px) 100vw, 1600px\" \/><\/figure>\n\n\n\n<p>Professor Yi-Chih Hsu also serves as Director of the Center for Cancer Diagnostics, Therapeutics Development, and Commercialization at Chung Yuan Christian University, where she has led a decade-long effort in advancing critical nanomedicine technologies. Her team\u2019s work in cancer drug delivery and nanoparticle-based formulation has steadily progressed from fundamental laboratory research to preclinical verification and GMP-compliant scalable manufacturing. The program has received sustained support from major government initiatives, including the NSTC Nanotechnology Flagship Project, multiple NSTC research and technology development grants, and other national funding programs. Professor Hsu\u2019s achievements have been widely recognized, earning several prestigious national awards such as the NSTC Future Tech Award and the National Innovation Award, and most recently, the 2025 National Innovation Award in Biopharmaceutical Advancement.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"832\" height=\"678\" src=\"https:\/\/eng.cycu.edu.tw\/wp-content\/uploads\/01-\u4e2d\u539f\u5927\u5b78\u6559\u6388\u8a31\u6bc5\u829d\uff08\u5de64\uff09\u5e36\u9818\u7814\u7a76\u5718\u968a\u6295\u5165\u5948\u7c73\u85e5\u7269\u95dc\u9375\u6280\u8853\u7814\u767c\uff0c\u63a8\u52d5\u6280\u8853\u5f9e\u5b78\u8853\u7814\u7a76\u9081\u5411\u81e8\u5e8a\u61c9\u7528\u3002.jpg\" alt=\"\" class=\"wp-image-34331\" srcset=\"https:\/\/eng.cycu.edu.tw\/wp-content\/uploads\/01-\u4e2d\u539f\u5927\u5b78\u6559\u6388\u8a31\u6bc5\u829d\uff08\u5de64\uff09\u5e36\u9818\u7814\u7a76\u5718\u968a\u6295\u5165\u5948\u7c73\u85e5\u7269\u95dc\u9375\u6280\u8853\u7814\u767c\uff0c\u63a8\u52d5\u6280\u8853\u5f9e\u5b78\u8853\u7814\u7a76\u9081\u5411\u81e8\u5e8a\u61c9\u7528\u3002.jpg 832w, https:\/\/eng.cycu.edu.tw\/wp-content\/uploads\/01-\u4e2d\u539f\u5927\u5b78\u6559\u6388\u8a31\u6bc5\u829d\uff08\u5de64\uff09\u5e36\u9818\u7814\u7a76\u5718\u968a\u6295\u5165\u5948\u7c73\u85e5\u7269\u95dc\u9375\u6280\u8853\u7814\u767c\uff0c\u63a8\u52d5\u6280\u8853\u5f9e\u5b78\u8853\u7814\u7a76\u9081\u5411\u81e8\u5e8a\u61c9\u7528\u3002-768x626.jpg 768w\" sizes=\"(max-width: 832px) 100vw, 832px\" \/><\/figure>\n\n\n\n<p>CYCU\u2019s Office of Industry\u2013Academia Collaboration and Patent Technology Transfer emphasized the university\u2019s commitment to advancing frontier scientific innovations toward real-world application. By integrating faculty research strengths, government-funded programs, and industry-driven product development needs, CYCU continues to establish a robust pipeline from scientific discovery to industrial adoption.<\/p>\n\n\n\n<p>CYCU President Ying-Ming Lee commended Professor Hsu and her team for their contributions to nanomedicine, noting that their work demonstrates the university\u2019s strong capabilities in bridging biomedical research with clinical translation. He also expressed gratitude to the NSTC and industry partners for their support, which has enabled the technology to progress beyond the laboratory toward clinical and industrial implementation. Looking ahead, CYCU will continue to promote interdisciplinary research and technology transfer, strengthening Taiwan\u2019s overall capacity in biomedical innovation and precision medicine.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Professor Yi-Chih Hsu of CYCU\u2019s Department of Biotechnology developed an innovative liposomal composite drug-loading platform that advances cancer drug delivery and nanoparticle formulation technologies. In November 2025, the platform was transferred to CYCU spin-off Hermez Nanomedicine, Inc., leading to a major licensing agreement that generated significant revenue for the university.<\/p>\n","protected":false},"author":7,"featured_media":34331,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[501],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>CYCU Professor Yi-Chih Hsu Transfers Innovative Nanomedicine Technology to Accelerate Precision Medicine Translation. - Chung Yuan Christian University<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/eng.cycu.edu.tw\/?p=34328\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CYCU Professor Yi-Chih Hsu Transfers Innovative Nanomedicine Technology to Accelerate Precision Medicine Translation. - Chung Yuan Christian University\" \/>\n<meta property=\"og:description\" content=\"Professor Yi-Chih Hsu of CYCU\u2019s Department of Biotechnology developed an innovative liposomal composite drug-loading platform that advances cancer drug delivery and nanoparticle formulation technologies. 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